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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adam Eaton | 2000-2012 | 69 | 44 | .611 | 4.39 | 428 | 112 | 2 | 0 | 11 | 1018.0 | 1002 | 496 | 85 | 342 | 724 |
| Anibal Echevarria | 2012-2029 | 70 | 106 | .398 | 4.93 | 527 | 187 | 3 | 2 | 61 | 1295.1 | 1493 | 710 | 102 | 534 | 634 |
| Charles Edmonson | 2010-2024 | 131 | 122 | .518 | 3.85 | 518 | 306 | 32 | 6 | 19 | 2263.0 | 2227 | 967 | 267 | 578 | 1548 |
| Brandon Edwards | 2009-2020 | 54 | 49 | .524 | 2.75 | 753 | 46 | 0 | 0 | 273 | 1008.0 | 903 | 308 | 75 | 157 | 838 |
| Joel Edwards | 2013-2018 | 41 | 37 | .526 | 3.70 | 255 | 73 | 4 | 1 | 17 | 647.1 | 635 | 266 | 61 | 262 | 449 |
| Joey Eischen | 1994-2007 | 39 | 22 | .639 | 3.79 | 557 | 2 | 0 | 0 | 11 | 532.0 | 503 | 224 | 14 | 238 | 416 |
| Scott Elarton | 1998-2000 | 28 | 13 | .683 | 4.14 | 100 | 47 | 2 | 0 | 3 | 373.2 | 349 | 172 | 0 | 147 | 308 |
| Bob Ellis | 2019-2031 | 63 | 65 | .492 | 5.19 | 361 | 179 | 3 | 2 | 2 | 1138.1 | 1275 | 657 | 180 | 463 | 927 |
| John Elmore | 2029-2033 | 14 | 14 | .500 | 4.16 | 275 | 0 | 0 | 0 | 33 | 314.0 | 285 | 145 | 24 | 212 | 253 |
| Nicolás Esparza | 2026-2032 | 15 | 14 | .517 | 5.85 | 152 | 31 | 0 | 0 | 4 | 303.0 | 288 | 197 | 41 | 225 | 311 |
| Felipe Espinoza | 2022-2033 | 60 | 49 | .550 | 5.09 | 493 | 106 | 1 | 0 | 10 | 1095.2 | 1366 | 620 | 176 | 191 | 533 |
| Rafael Espinoza | 2030-2033 | 6 | 9 | .400 | 5.00 | 136 | 1 | 0 | 0 | 2 | 217.2 | 193 | 121 | 36 | 156 | 221 |
| Shawn Estes | 1995-2006 | 77 | 78 | .497 | 4.50 | 270 | 217 | 10 | 7 | 1 | 1369.1 | 1326 | 685 | 15 | 718 | 1062 |
| José Estrada | 2019-2020 | 0 | 0 | .000 | 5.06 | 9 | 0 | 0 | 0 | 0 | 10.2 | 15 | 6 | 1 | 4 | 6 |
| Damon Evans | 2031-2033 | 11 | 11 | .500 | 3.94 | 67 | 43 | 0 | 0 | 7 | 265.0 | 230 | 116 | 26 | 132 | 210 |
| Elvis Evans | 2030-2033 | 11 | 5 | .688 | 3.46 | 164 | 0 | 0 | 0 | 5 | 174.1 | 146 | 67 | 8 | 128 | 179 |
| Clint Everts | 2009-2017 | 16 | 20 | .444 | 5.55 | 242 | 5 | 0 | 0 | 3 | 325.2 | 336 | 201 | 59 | 218 | 324 |
| Brian Ewing | 2033-2033 | 11 | 10 | .524 | 4.51 | 31 | 31 | 2 | 1 | 0 | 183.2 | 194 | 92 | 28 | 65 | 181 |
| Scott Eyre | 1997-2009 | 64 | 61 | .512 | 4.17 | 526 | 129 | 0 | 0 | 17 | 1117.0 | 1075 | 518 | 51 | 486 | 779 |
