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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Warren Piche | 11.4 | 2011-2030 | |
| 2 | Randy Johnson | 11.2 | 1988-2004 | |
| 3 | Camilo Vasquez* | 10.1 | 2006-2021 | |
| 3 | Trevor Hoffman | 10.1 | 1993-2006 | |
| 5 | Hsin-ta Shiu# | 10.0 | 2023-2033 | |
| 6 | Octavio Dotel | 9.9 | 1999-2012 | |
| 6 | Javier Rivera# | 9.9 | 2020-2033 | |
| 8 | Robb Nen | 9.8 | 1993-2008 | |
| 9 | Sam Lahoda | 9.5 | 2018-2033 | |
| 10 | Hernan Saenz | 9.4 | 2009-2029 | |
| 11 | Roy Bendall# | 9.2 | 2024-2032 | |
| 11 | Kerry Wood | 9.2 | 1998-2013 | |
| 13 | John Morris | 9.1 | 2017-2030 | |
| 13 | Jorge Franco# | 9.1 | 2018-2033 | |
| 13 | Edward Burdge | 9.1 | 2009-2026 | |
| 16 | Justin Jones* | 8.9 | 2008-2026 | |
| 16 | Garrett Berger | 8.9 | 2007-2022 | |
| 16 | Luis Pacheco | 8.9 | 2015-2026 | |
| 16 | Curt Schilling | 8.9 | 1988-2004 | |
| 20 | Roy Oswalt | 8.7 | 2001-2012 | |
| 20 | Hideo Nomo | 8.7 | 1995-2005 | |
| 20 | Jesse Foppert* | 8.7 | 2003-2022 | |
| 20 | Mark Prior | 8.7 | 2002-2019 | |
| 20 | Dan Plesac | 8.7 | 1986-2003 | |
| 20 | Macay McBride | 8.7 | 2006-2025 | |
| 26 | Justin Barber# | 8.6 | 2023-2032 | |
| 27 | Josh Beckett | 8.5 | 2001-2016 | |
| 27 | Pedro Silva | 8.5 | 2016-2030 | |
| 27 | Brady Ash | 8.5 | 2017-2026 | |
| 30 | José López# | 8.3 | 2028-2033 | |
| 30 | Ramiro Cruz# | 8.3 | 2026-2033 | |
| 32 | Jeremy Griffiths | 8.2 | 2003-2016 | |
| 32 | Jesse Orosco | 8.2 | 1979-2002 | |
| 32 | Melvin Valdez | 8.2 | 2007-2019 | |
| 32 | Byung-hyun Kim | 8.2 | 1999-2016 | |
| 32 | Adrian Dunn# | 8.2 | 2024-2033 | |
| 37 | Mike Megrew | 8.1 | 2008-2023 | |
| 37 | Jarrod Thatcher# | 8.1 | 2021-2032 | |
| 37 | Mitch Talbot | 8.1 | 2005-2021 | |
| 37 | Adam Wainwright | 8.1 | 2004-2014 | |
| 37 | Blair Johnson | 8.1 | 2009-2028 | |
| 42 | John Williams# | 8.0 | 2025-2033 | |
| 42 | Robert Rogers# | 8.0 | 2020-2033 | |
| 42 | Jose Rojas | 8.0 | 2004-2014 | |
| 42 | Elder Rebocho | 8.0 | 2019-2028 | |
| 42 | Juan Machado# | 8.0 | 2018-2033 | |
| 47 | Manuel Morán | 7.9 | 2024-2032 | |
| 47 | John Smoltz | 7.9 | 1988-2006 | |
| 47 | Juan Gonzáles# | 7.9 | 2026-2033 | |
| 47 | Arthur Ginn | 7.9 | 2014-2028 | |
| 51 | Zach Duke* | 7.8 | 2007-2026 | |
| 51 | Ricardo Torres | 7.8 | 2015-2029 | |
| 51 | John Bale | 7.8 | 1999-2016 | |
| 54 | Manny Parra | 7.7 | 2008-2020 | |
| 54 | Carlos Zambrano | 7.7 | 2001-2017 | |
| 54 | Michael Bodden | 7.7 | 2013-2025 | |
| 54 | Rusty Tucker | 7.7 | 2005-2021 | |
| 58 | Reese House# | 7.6 | 2025-2033 | |
| 58 | Benton Grant | 7.6 | 2013-2025 | |
| 58 | Claudio Vargas* | 7.6 | 2003-2020 | |
| 58 | Steven Dawson | 7.6 | 2018-2029 | |
| 58 | Wade Miller | 7.6 | 1999-2014 | |
| 58 | Jeff Fassero | 7.6 | 1991-2003 | |
| 58 | Denny Bautista | 7.6 | 2007-2018 | |
| 65 | Randy Wolf | 7.5 | 1999-2011 | |
| 65 | Mark Guthrie | 7.5 | 1989-2004 | |
| 65 | Brandon Edwards | 7.5 | 2009-2020 | |
| 65 | Matt Ford | 7.5 | 2005-2019 | |
| 65 | Jake Price | 7.5 | 2017-2031 | |
| 65 | Claude Mosley# | 7.5 | 2026-2033 | |
| 65 | Chris Capuano | 7.5 | 2003-2013 | |
| 65 | Al Leiter | 7.5 | 1987-2004 | |
| 73 | Takeji Maruyama | 7.4 | 2025-2032 | |
| 73 | Duane Golden | 7.4 | 2010-2027 | |
| 73 | Jimmy Journell | 7.4 | 2003-2015 | |
| 73 | Otis Servantes | 7.4 | 2012-2026 | |
| 73 | Ernest Fountain# | 7.4 | 2019-2033 | |
| 73 | Ty Howington | 7.4 | 2006-2022 | |
| 73 | Darren Dreifort | 7.4 | 1994-2006 | |
| 73 | Jake Peavy | 7.4 | 2002-2014 | |
| 81 | Bob Ellis | 7.3 | 2019-2031 | |
| 82 | Daniel Soto | 7.2 | 2014-2026 | |
| 82 | Bob Harmon# | 7.2 | 2022-2033 | |
| 82 | Mark Allen | 7.2 | 2015-2029 | |
| 82 | Javier Vazquez | 7.2 | 1998-2012 | |
| 82 | Oliver Perez | 7.2 | 2002-2011 | |
| 82 | Mike Gosling | 7.2 | 2006-2018 | |
| 88 | Justin Wechsler | 7.1 | 2006-2014 | |
| 88 | Randy Smith | 7.1 | 2005-2026 | |
| 88 | Gabe White | 7.1 | 1994-2010 | |
| 88 | Tyler Johnson* | 7.1 | 2003-2018 | |
| 88 | Bobby Basham* | 7.1 | 2003-2018 | |
| 88 | Mike Connolly | 7.1 | 2008-2022 | |
| 88 | Miguel Angel Puopolo# | 7.1 | 2021-2033 | |
| 88 | John Franco | 7.1 | 1984-2003 | |
| 88 | Michael Perales | 7.1 | 2011-2025 | |
| 88 | Matt Clement | 7.1 | 1998-2010 | |
| 98 | Jason Schmidt | 7.0 | 1995-2009 | |
| 98 | Ben Allen | 7.0 | 2015-2029 | |
| 98 | Shawn Estes | 7.0 | 1995-2006 |
