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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saito, Yasuo | SP | Mill Basin Kings | 20 | 10/21/2014 | Saitama | JPN | Switch | Right | 6' 5" | 200 lbs | - |
| Sakurai, Yasuhiro | SP | Colorado Springs Gangsters | 19 | 10/07/2015 | Kyoto | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Salazar, Alfonso | CF | Thunder Bay Lightning | 21 | 04/07/2013 | Camagüey | CUB | Left | Left | 6' 2" | 180 lbs | - |
| Salazar, David | RP | Colorado Springs Gangsters | 21 | 08/22/2013 | Pedernales | DOM | Right | Left | 5' 11" | 165 lbs | - |
| Salinas, Gabriel | 1B | Albuquerque Isotopes | 30 | 08/26/2004 | Unknown | MEX | Right | Right | 6' 0" | 240 lbs | - |
| Sánchez, Arturo | RP | Millers Creek Bobcats | 23 | 04/28/2011 | Brooklyn | USA | Left | Left | 6' 2" | 205 lbs | - |
| Sánchez, Augusto | RF | La Jolla Rebels | 22 | 08/11/2012 | Las Tunas | CUB | Switch | Right | 6' 3" | 190 lbs | - |
| Sánchez, Fernando | 1B | Tijuana Toros | 19 | 03/04/2015 | Moca | DOM | Right | Right | 6' 8" | 210 lbs | - |
| Sánchez, José | RP | Tijuana Toros | 20 | 08/08/2014 | Bayamón | PUR | Left | Right | 6' 0" | 170 lbs | - |
| Sánchez, Junior | SP | Mill Basin Kings | 20 | 11/14/2014 | Valencia | VEN | Switch | Left | 6' 5" | 205 lbs | - |
| Sánchez, Lorenzo | RP | Colorado Springs Gangsters | 24 | 06/05/2010 | San Jose | USA | Right | Right | 6' 0" | 185 lbs | - |
| Sánchez, Lúcio | SS | Free Agent | 30 | 07/07/2004 | Maplewood | USA | Right | Right | 6' 0" | 220 lbs | - |
| Sánchez, Pedro | 3B | Free Agent | 26 | 10/05/2008 | Unknown | MEX | Right | Right | 6' 0" | 190 lbs | - |
| Sánchez, Rafael | SP | Missoula Moose Drool | 22 | 12/20/2012 | Santa Lucía Cotzumalguapa | GUA | Left | Right | 6' 3" | 195 lbs | - |
| Sánchez, Roberto | 3B | Tijuana Toros | 19 | 07/07/2015 | Ponce | PUR | Right | Right | 6' 0" | 180 lbs | - |
| Santos, Raúl | CF | Free Agent | 25 | 08/26/2009 | San Juan | PUR | Right | Left | 6' 0" | 190 lbs | - |
| Saunders, Warren | 1B | Mill Basin Kings | 19 | 01/18/2015 | Melbourne | AUS | Right | Right | 6' 2" | 210 lbs | - |
| Seki, Kijuro | RP | Free Agent | 24 | 12/12/2010 | Ina | JPN | Right | Right | 6' 4" | 200 lbs | - |
| Serrano, Manuel | CF | Albuquerque Isotopes | 25 | 09/29/2009 | Walpole | USA | Right | Left | 5' 11" | 185 lbs | - |
| Serrano, Rafael | CF | La Jolla Rebels | 24 | 06/25/2010 | Winchester | USA | Left | Left | 6' 0" | 190 lbs | - |
| Shapland, Mark | C | Albuquerque Isotopes | 25 | 10/01/2009 | Fresno | USA | Right | Right | 6' 1" | 220 lbs | - |
| Shelton, Chris | RP | Mill Basin Kings | 25 | 06/09/2009 | Chicago | USA | Right | Right | 6' 3" | 225 lbs | - |
| Sierra, Peter | RP | Ocean Park Windwalkers | 27 | 11/08/2007 | Moses Lake | USA | Left | Left | 6' 1" | 210 lbs | - |
| Smith, Jacob | RP | Ocean Park Windwalkers | 21 | 02/23/2013 | Itoman | JPN | Left | Right | 6' 1" | 185 lbs | - |
| Smith, Jeffrey | C | Albuquerque Isotopes | 19 | 02/18/2015 | Cutler Ridge | USA | Right | Right | 5' 8" | 165 lbs | - |
| Smith, Peto | RP | Free Agent | 24 | 12/18/2010 | Virginia | RSA | Right | Right | 6' 7" | 215 lbs | - |
| Sosa, Manny | RP | Millers Creek Bobcats | 23 | 02/02/2011 | Moca | DOM | Left | Left | 5' 11" | 180 lbs | - |
| Sosa, Marcos | RP | Mill Basin Kings | 24 | 07/05/2010 | Santiago | DOM | Left | Left | 6' 2" | 200 lbs | - |
| Sugimoto, Kyuso | RF | Mill Basin Kings | 16 | 04/03/2018 | Matsuyama | JPN | Right | Right | 6' 2" | 165 lbs | - |
| Sun, An-te-hai | SP | Thunder Bay Lightning | 19 | 05/29/2015 | Toronto | CAN | Right | Right | 6' 3" | 195 lbs | - |
| Suzuki, Isei | RP | Free Agent | 24 | 11/16/2010 | Gobo | JPN | Right | Right | 6' 7" | 210 lbs | - |
